WUM scientists as the co-authors of groundbreaking research in nuclear medicine and particle physics

Prof. Jolanta Kunikowska, Prof. Leszek Królicki and a team from the Department of Nuclear Medicine UCC MUW took part in an innovative research project using a new diagnostic parameter - positronium lifetime - for brain tumor imaging. This was the first “positronium” imaging in the world. The project was led by the J- PET team from the Department of Experimental Particle Physics of the Jagiellonian University, led by Prof. Paweł Moskal and Prof. Ewa Stępień.

The study was designed to assess the feasibility of imaging cancerous lesions with a “positronium biomarker.” It was performed on a prototype J-PET apparatus - a novel tomograph developed and built by scientists from the Jagiellonian University. The prototype went to the Department of Nuclear Medicine UCC MUW, where specialists from this department performed the first imaging of a patient with a brain tumor.

An important part of the study was to compare the lifetime of positronium in healthy brain tissue and cancerous lesions, in this case glioma. The study showed that the average lifetime of positronium in glioma is significantly shorter than in healthy brain tissue. The findings suggest that positronium imaging could be used to increase the specificity of PET diagnostics in tissue pathology in vivo.

An article on the groundbreaking research has just been published in the prestigious journal Science Advances. It is available at the link

- Hopefully, this discovery will allow us to better diagnose patients with cancerous lesions in the future - says Prof. Jolanta Kunikowska.

As Prof. Kunikowska emphasized in an interview with MUW, currently specialists are already treating thyroid cancer, prostate cancer and neuroendocrine tumors with nuclear medicine methods. And ongoing research gives hope that many other cancers will soon be beaten in this way.

We encourage you to read the entire conversation available at the link