According to current knowledge, a kinase called CDC7 is essential for cell division in all studied organisms: from yeast to humans. At the molecular level, CDC7 initiates DNA replication. During the lecture, Professor Piotr Siciński - pathologist and molecular biologist from Harvard Medical School (Department of Cancer Biology, Dana-Farber Cancer Institute) will talk about his team's research verifying the above model. They generated cells and mice in which the CDC7 protein can be specifically and temporally degraded. Studies have shown that a different mechanism operates in mammalian cells that allows DNA replication without the CDC7 protein.
The lecture will be held in English. Attendance at the lecture is free. Willingness to participate should be reported to biurojakosci@wum.edu.pl by April 28 this year.
The number of places is limited. Participation is determined on a first-come, first-served basis.